Tremor Video helps advertisers deliver impactful stories across all screens through the power of innovative video technology combined with advanced data and captivating creative. Tremor Video is one of the largest and most innovative video advertising companies in North America, providing clients with market-leading Connected TV, in-stream and in-app solutions.
Tremors are abnormal movements of the body that occur because of conditions affecting the nervous system. Some tremors occur at rest and become less apparent with activity. They are referred to as rest tremors. The classic rest tremor is from Parkinson's disease.Some tremors are most apparent as the extremity is lifted against gravity and not moving toward a target (for. Get directions, reviews and information for Tremor Media Inc in San Francisco, CA. Tremor Media Inc 50 California St San Francisco CA 94111. Reviews (415) 277-5923 Website. Menu & Reservations Make Reservations. Order Online Tickets Tickets See Availability Directions.
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About Us
Tremor International Ltd. is a global leader in advertising technologies with operations in more than 60 countries. Tremor's shares have been traded on the London Stock Exchange since 2014 (AIM: TRMR).
Tremor offers digital advertising solutions which leverage the latest video, native, and display technology to reach the most valuable users for every app, service, and brand. Tremor works with more than 450 advertisers including Amazon, Disney, Twitter, OpenTable, Expedia, and Zynga, and more than 50,000 supply and publishing partners worldwide.
Tremor International - Strong Track Record of Growth
Year Ended 31 December 2019
138.5MGross Profit76.9MNet Cash37.05 centsAdjusted Diluted EPSManagement
Ofer Druker on LinkedInOfer Druker, Chief Executive Officer
A pioneer in digital media, with nearly 20 years of industry experience. Ofer joined the Tremor group in 2017 after co-founding Matomy Media Group, Ltd. (LSE: MTMY, TASE: MTMY.TA). Matomy Media Group is a global media company that began as a start-up and has since gone public.
Sagi Niri on LinkedInSagi Niri, Chief Financial Officer
Experienced director with over 20 years in finance and leadership roles, including over nine years as CFO, then CEO, of London-listed Matomy Media Group. Sagi joined the Company in 2020 and is a member of the Institute of Certified Public Accountants in Israel.
Yaniv Carmi on LinkedInYaniv Carmi, Chief Operating Officer
An experienced finance professional having served as a tax and audit senior at KPMG Israel, and several consultant roles for medium to large private and public companies, including due diligence participation in M&As and IPOs. CPA & MBA. Yaniv has been with the Company since 2010.
Tal Mor on LinkedInTal Mor, Chief Technology Officer
Software engineering expert with over 20 years of managing large teams, specializing in software craftsmanship and growth techniques. Experienced in the orchestration of software development and QA teams. Involved in BlueSnap (formerly Plimus) engineering prior to their acquisition and joined Tremor in 2017.
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Karim Rayes on LinkedInKarim Rayes, Chief Product Officer
Product expert with experience in publisher development and product management. 12+ years of experience in digital media, an expert in publishing, programmatic advertising, media buying, and business development & affiliate marketing and management. Karim joined RhythmOne (a division of Tremor), in 2012.
Jay Baum on LinkedInJay Baum, Chief Commercial Officer
Business leader with experience in managing data partnerships, data operations, supply operations, creative, and publisher and corporate development. Works to craft new and ongoing business deals and drive new revenue opportunities.
Anthony Flaccavento on LinkedInAnthony Flaccavento, Head of Tremor Video
Business executive with extensive expertise in driving revenue and client success. Previously held multiple sales leadership roles with high profile consumer content brands and media companies including Complex, Maxim Magazine, and Athlon Sports.
Assaf Suprasky on LinkedInAssaf Suprasky, Head of Performance
Experienced executive with a demonstrated history of leading business and technology ventures in the ad tech space. He has managed operational teams globally, supervised numerous acquisitions and played a pivotal role in leading IPO processes.
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Jackie Orris on LinkedInJackie Orris, SVP HR
Human resources expert with over 20 years of experience in leading teams across the entire employee lifecycle. She’s held leadership roles at companies that range from startups to Fortune 500 and most recently at LiveIntent, Newscred, and Experian. Jackie joined Tremor in 2017.
Amy Rothstein on LinkedInAmy Rothstein, Chief Legal Officer & Head of Corporate Development
Experienced legal professional having held legal and corporate business positions in large multinational corporations, investment management groups, and legal firms. Experienced in mergers and acquisitions, corporate operations, and corporate law. JD and LLM.
Overview
In this article, the author reviews new studies related to the pathogenesis of essential tremor, including Purkinje cell pathology as well as LINGO1 and SLC1A2 genes. Clinical diagnosis of tremor disorders and treatment strategies for essential tremor are described in detail.
Key points
• Two subtypes of essential tremor pathology have been identified: a primarily cerebellar variant with Bergmann gliosis and Purkinje cell torpedoes, and a Lewy body variant. |
• Propranolol and primidone are useful first-line medications for essential tremor. |
• Deep brain stimulation surgery continues to be useful for severe, medication-resistant tremor. |
Historical note and terminology
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The history of tremor can be roughly divided into 2 phases. The first and largely descriptive phase began in the 19th century; clinicians were able to recognize the principal manifestations of tremor and characterize and classify different forms of tremor based on clinical patterns and their relationships with known pathologies. GF Most provided 1 of these reports of action tremor in 1836. The first known use of the term “essential tremor” was traced to Pietro Burresi in 1874 (Louis 2008). The names of Romberg, Parkinson, Gowers, and Charcot all contributed extensively to our knowledge and laid the groundwork for the second phase. Charcot collected handwriting samples from his patients and differentiated between tremulous handwriting in essential tremor and micrographic handwriting in Parkinson disease (Goetz 2007). Gowers described rest tremor at the metacarpal-phalangeal joints as someone beating a small drum (Goetz 2007).
The second phase began in the latter part of this century with the explosion of newer technologies that were able to further identify the pathophysiology of tremor. This explosion also contributed to our further ability to carefully classify clinical syndromes not only in terms of their phenomenology and pathology but also their neurophysiology. This phase has led to significant improvements and advances in treatment culminating presently with surgical therapies and deep brain stimulation.
Descriptions of the contributions of early American investigators to the understanding of tremors (Lanska 2000), and documentation of essential tremor in Samuel Adams, an early American patriot (Louis 2001c), provide an interesting historical perspective on tremor.
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The diagnosis, classification, etiology, pathophysiology, and treatment have been controversial in the past, but progress has been made in all of these parameters. The 2018 Consensus Statement from the International Parkinson and Movement Disorder Society retains characteristic tremor syndromes but also evaluates them on clinical characteristics on Axis 1 and etiology on Axis 2 (Bhatia et al 2018).
| Image: Axis 1 and Axis 2 of tremor syndromes |
The concept of essential tremor as a single, monosymptomatic entity has changed over time (Espay et al 2017; Louis 2018). The 2018 consensus statement addresses this heterogeneity by recognizing that there may be additional features such as dystonia, bradykinesia, cognitive impairment (Axis 1), and a heterogenous etiology (Axis 2). This improved classification system should allow for more success in clinical research of essential tremor. Given the significant potential for disability in both social and occupational settings due to tremor (Elias and Shah 2014), the word “benign” was removed from the term “benign essential tremor” (Louis and Okun 2011).